Sequencing Technology Development

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Project Title Project Number Contact PI / Project Leader Organization Name Publications TDCC Status
Synthetic mRNA Control Set for Nanopore-Based Pseudouridine Modification Profiling in Human Transcriptomes HG012856 ROUHANIFARD, SARA NORTHEASTERN UNIVERSITY View publication Active
Development of Next-Generation Mass Spectrometry-based de novo RNA Sequencing for all Modifications HG012853 ZHANG, SHENGLONG NEW YORK INST OF TECHNOLOGY View publication Active
Sequencing the Mono-Methylated Derivatives of Cytidine HG012850 ERVIN, ERIC ELECTRONIC BIOSCIENCES, INC. View publication Active
METHYL-SENTRY: Proposed feasibility study of a nanopore diagnostic tool with rapid automated measurement of cell free DNA methylation state for clinical cancer evaluation HG012724 DIPAOLO, BRIAN GOEPPERT, LLC View publication Active
Single molecule DNA/RNA sequencing technology based on a parallel Raman scattering readout in a coupled nanochannel/nanopore system HG011608 BRUECK, STEVEN ARMONICA TECHNOLOGIES, INC. View publication Active
Telomere-to-telomere assemblies of human genomes HG011274 MIGA, KAREN HAYDEN UNIVERSITY OF CALIFORNIA SANTA CRUZ View publication Active
Enzymeless, controlled electrostatic ratcheting in solid-state nanopores HG012413 SHEPARD, KENNETH L (contact); DRNDIC, MARIJA COLUMBIA UNIV NEW YORK MORNINGSIDE View publication Active
Advanced Parallel Readers for DNA Sequencing Through a 2D Nanopore HG012395 DRNDIC, MARIJA UNIVERSITY OF PENNSYLVANIA View publication Active
Novel Chemical Probes for Sequencing Multiple DNA Modifications at Single-Nucleotide Resolution HG012412 ZHAO, LINLIN UNIVERSITY OF CALIFORNIA RIVERSIDE View publication Active
Two readers for RNA HG012364 SCHIBEL, ANNA ELECTRONIC BIOSCIENCES, INC. View publication Active
Nanoscale Tools for Inosine Sequencing HG012409 ERVIN, ERIC ELECTRONIC BIOSCIENCES, INC. View publication Active
Ion Fountain Nanopore Readers for High-Resolution DNA and RNA Sequencing HG011689 WANUNU, MENI NORTHEASTERN UNIVERSITY View publication Active
Conductance Fluctuations: A New Approach to Sequencing? HG010522 LINDSAY, STUART ARIZONA STATE UNIVERSITY-TEMPE CAMPUS View publication Active
High Accuracy Nanopore Sequencing HG005115 GUNDLACH, JENS UNIVERSITY OF WASHINGTON View publication Active
Direct Determination of Multiple Specific Forms of DNA Chemical Modifications in Human Genome HG011095 FANG, GANG ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI View publication Active
Direct nanopore detection of modified RNA to probe structure and dynamics HG010538 TIMP, WINSTON GEORGE JOHNS HOPKINS UNIVERSITY View publication Active
Exploring 3Dpol for RNA sequencing in real time HG011120 HOU, YA-MING THOMAS JEFFERSON UNIVERSITY View publication Active
Single-cell direct RNA sequencing using electrical zero-mode waveguides and engineered reverse transcriptases HG011087 WANUNU, MENI NORTHEASTERN UNIVERSITY View publication Active
Sequencing by Direct Electrical Measurements of Polymerase Fluctuations HG011079 LINDSAY, STUART ARIZONA STATE UNIVERSITY-TEMPE CAMPUS View publication Active
Improving biological nanopores for precision nucleic acid sequencing using a computational microscope HG011741 AKSIMENTIEV, ALEKSEI (contact); CHEN, MIN UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN View publication Active
Single-Molecule Electronic Nucleic Acid Sequencing-by-Synthesis Using Novel Tagged Nucleotides and Nanopore Constructs HG010514 JU, JINGYUE (contact); CHURCH, GEORGE M; KALACHIKOV, SERGEY COLUMBIA UNIV NEW YORK MORNINGSIDE View publication Active
DNA barcoding via multi-scan and step control in dual-pore tug-of-war HG011236 REISNER, WALTER (contact); DUNBAR, WILLIAM BRUCE; SLADEK, ROBERT MCGILL UNIVERSITY View publication Complete
On-site, high-fidelity target sequencing and absolute quantitation for HIV-1 surveillance HG010318 KIM, SANGGU OHIO STATE UNIVERSITY View publication Complete
Single-chain MspA for nanopore sequencing of DNA HG010543 NIEDERWEIS, MICHAEL UNIVERSITY OF ALABAMA AT BIRMINGHAM View publication Complete
Novel sequencing by synthesis platform to greatly reduce the cost of nucleic acid sequencing HG010558 PRATT, MARK ROBIN ULTIMA GENOMICS, INC. View publication Complete
RNA Sequencing Via Single Reverse Transcript Assessments HG011070 GERMAN, SEAN ELECTRONIC BIOSCIENCES, INC. View publication Complete
Nanopore Based Direct BAT-25 Microsatellite Sequencing HG010435 SCHIBEL, ANNA ELECTRONIC BIOSCIENCES, INC. View publication Complete
Improving Throughput of Long Reads with High Consensus Base Accuracy to Resolve Repetitive DNAs HG010548 MIGA, KAREN HAYDEN UNIVERSITY OF CALIFORNIA SANTA CRUZ View publication Complete
LC/MS-Based Direct RNA Sequencing with Concomitant Capability to Sequence Multiple Base Modifications at Single-base Resolution HG011099 ZHANG, SHENGLONG NEW YORK INST OF TECHNOLOGY View publication Complete
DNA Sequencing with novel 2D FET-nanopore devices HG010536 DRNDIC, MARIJA UNIVERSITY OF PENNSYLVANIA View publication Complete
Exonuclease Epigenetic Sequencing HG010049 ERVIN, ERIC ELECTRONIC BIOSCIENCES, INC. View publication Complete
High-accuracy, long-range sequencing for HIV-1 genotyping HG010108 KIM, SANGGU OHIO STATE UNIVERSITY View publication Complete
Computational Design Engine for Accurate and Efficient Sequencing of DNA and RNA HG002776 MUTHUKUMAR, MURUGAPPAN UNIVERSITY OF MASSACHUSETTS AMHERST View publication Complete
Chemically Tuned Silicon Nitride Nanopores for Nucleic Acid Sequencing HG011096 DWYER, JASON RODGER UNIVERSITY OF RHODE ISLAND View publication Complete
Novel sequencing by synthesis chemistry to further reduce the cost of nucleic acid sequencing HG011060 MAZUR, DANIEL JOSEPH ULTIMA GENOMICS, INC. View publication Complete
A Unified Nanopore Platform for Direct Sequencing of Individual Full Length RNA Strands Bearing Modified Nucleotides HG010053 AKESON, MARK A UNIVERSITY OF CALIFORNIA SANTA CRUZ View publication Complete
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