Project Title |
Project Number |
Contact PI / Project Leader |
Organization Name |
Publications |
TDCC Status |
A quick, and robust, and unbiased platform for circular RNAs isolation, discovery and profiling. |
HG013073 |
KHADE, PRASHANT K |
RIBO-THERAPEUTICS LLC |
View publication |
Active |
Single-molecule protein sequencing by detection and identification of N-terminal amino acids |
HG012960 |
ESTANDIAN, DANIEL MASAO |
GLYPHIC BIOTECHNOLOGIES, INC. |
View publication |
Active |
Controlled Protein Translocation in Nanopores for Sequencing Applications |
HG012962 |
SCHIBEL, ANNA |
ELECTRONIC BIOSCIENCES, INC. |
View publication |
Active |
Post-translational phenotypic profiling through nucleotide barcode sequencing |
HG012991 |
INGOLIA, NICHOLAS T |
UNIVERSITY OF CALIFORNIA BERKELEY |
View publication |
Active |
Decoding global RNP topologies in splicing regulation |
HG012928 |
LU, ZHIPENG |
UNIVERSITY OF SOUTHERN CALIFORNIA |
View publication |
Active |
Asymmetric Single-Chain MspA nanopores for electroosmotic stretching and sequencing proteins |
HG012553 |
WANUNU, MENI (contact); AKSIMENTIEV, ALEKSEI ; CHEN, MIN ; NIEDERWEIS, MICHAEL |
NORTHEASTERN UNIVERSITY |
View publication |
Active |
Chemistry for next-generation single-molecule fluorosequencing technology 2.0 |
HG012941 |
RAJ, MONIKA |
EMORY UNIVERSITY |
View publication |
Active |
Photo-Fragmentation Methods for Single-Molecule Protein Sequencing by Nanopore Mass Spectrometry |
HG012938 |
STEIN, DEREK |
BROWN UNIVERSITY |
View publication |
Active |
Mapping proximal and distal splicing-regulatory elements |
HG012359 |
ZHANG, CHAOLIN |
COLUMBIA UNIVERSITY HEALTH SCIENCES |
View publication |
Active |
Light-Seq: Spatially targeted profiling of transcriptomic states in cells and tissue |
HG012926 |
YIN, PENG |
HARVARD UNIVERSITY |
View publication |
Active |
Synthetic mRNA Control Set for Nanopore-Based Pseudouridine Modification Profiling in Human Transcriptomes |
HG012856 |
ROUHANIFARD, SARA |
NORTHEASTERN UNIVERSITY |
View publication |
Active |
Rapid NGS Method for Mapping of the Epitranscriptome |
HG012534 |
STENGEL, GUDRUN |
ALIDA BIOSCIENCES, INC. |
View publication |
Active |
Developing a robust method for analyzing transcription factor mediated chromatin interactions |
HG012627 |
CHEN, LIN |
UNIVERSITY OF SOUTHERN CALIFORNIA |
View publication |
Active |
In vivo Perturb-map: scalable genetic screens with single-cell and spatial resolution in intact tissues |
HG012819 |
JIN, XIN |
SCRIPPS RESEARCH INSTITUTE, THE |
View publication |
Active |
Next generation massively multiplexed combinatorial genetic screens |
HG012351 |
MALI, PRASHANT (contact); IDEKER, TREY |
UNIVERSITY OF CALIFORNIA, SAN DIEGO |
View publication |
Active |
Multiplexed Analysis of the Epitranscriptome |
HG012170 |
STENGEL, GUDRUN |
ALIDA BIOSCIENCES, INC. |
View publication |
Active |
Mechanisms of Transcriptional Control Revealed by Nascent Transcript Sequencing |
HG007173 |
CHURCHMAN, LEE STIRLING |
HARVARD MEDICAL SCHOOL |
View publication |
Active |
Scalable, quantitative, single-cell CRISPR screens |
HG012230 |
NORMAN, THOMAS |
SLOAN-KETTERING INST CAN RESEARCH |
View publication |
Active |
Bi-functional photo-crosslinking (BFPX) for genome-wide study of protein-nucleic acid interactions |
HG012419 |
CHEN, LIN |
UNIVERSITY OF SOUTHERN CALIFORNIA |
View publication |
Active |
Development of GenomeBuild as a Universal Method to Synthesize Genomes |
HG012745 |
WARREN, CHRISTOPHER L (contact); OZERS, MARY SZATKOWSKI |
PROTEOVISTA, LLC |
View publication |
Active |
The Assemblatron |
HG012743 |
BOEKE, JEF D |
NEW YORK UNIVERSITY SCHOOL OF MEDICINE |
View publication |
Active |
Development of Next-Generation Mass Spectrometry-based de novo RNA Sequencing for all Modifications |
HG012853 |
ZHANG, SHENGLONG |
NEW YORK INST OF TECHNOLOGY |
View publication |
Active |
Advancing an Innovative NGS Approach to Discover and Investigate Histone Tail Proteolysis |
HG012833 |
RICE, JUDD C |
UNIVERSITY OF SOUTHERN CALIFORNIA |
View publication |
Active |
Sequencing the Mono-Methylated Derivatives of Cytidine |
HG012850 |
ERVIN, ERIC |
ELECTRONIC BIOSCIENCES, INC. |
View publication |
Active |
Extensive multiplexing of protein nucleic-acid interactions to comprehensively study gene expression regulation from chromatin to mRNA degradation |
HG012216 |
JOVANOVIC, MARKO (contact); GUTTMAN, MITCHELL |
COLUMBIA UNIV NEW YORK MORNINGSIDE |
View publication |
Active |
Mapping the dynamics of mouse neurogenesis in autism models using high-resolution genomic barcoding technologies |
HG012357 |
KALHOR, REZA |
JOHNS HOPKINS UNIVERSITY |
View publication |
Active |
METHYL-SENTRY: Proposed feasibility study of a nanopore diagnostic tool with rapid automated measurement of cell free DNA methylation state for clinical cancer evaluation |
HG012724 |
DIPAOLO, BRIAN |
GOEPPERT, LLC |
View publication |
Active |
DNA 3.0: Development of a novel, efficient and cost-effective enzymatic process for synthesis of DNA oligonucleotides |
HG010995 |
ZIELER, HELGE |
PRIMORDIAL GENETICS, INC |
View publication |
Active |
Single molecule DNA/RNA sequencing technology based on a parallel Raman scattering readout in a coupled nanochannel/nanopore system |
HG011608 |
BRUECK, STEVEN |
ARMONICA TECHNOLOGIES, INC. |
View publication |
Active |
Targets and functions of the mammalian snoRNAome |
HG012780 |
PAN, TAO (contact); HE, CHUAN |
UNIVERSITY OF CHICAGO |
View publication |
Active |
CRISPR-based genome tagging of iPS Cells for stain-free multicolor live cell analysis |
HG012241 |
PEREZ-LEAL, OSCAR |
TEMPLE UNIV OF THE COMMONWEALTH |
View publication |
Active |
Single-cell and single-molecule profiling of protein-DNA interactions by MACHA |
HG012423 |
POTT, SEBASTIAN (contact); IKEGAMI, KOHTA |
UNIVERSITY OF CHICAGO |
View publication |
Active |
Single molecule oligopeptide fingerprinting based on templated self-assembly of oligonucleotide structures |
HG012543 |
HESS, HENRY |
COLUMBIA UNIV NEW YORK MORNINGSIDE |
View publication |
Active |
Designed nanopores for single-molecule protein sequencing |
HG012554 |
MAGLIA, GIOVANNI |
GRONINGEN UNIVERSITY |
View publication |
Active |
Structural profiling of native proteins using fluorosequencing, a single molecule protein sequencing technology |
HG012561 |
SWAMINATHAN, JAGANNATH |
ERISYON INC |
View publication |
Active |
Ultrasensitive multiomic platform using epitope-targeted DNA methylation mapping |
HG011875 |
KEOGH, MICHAEL-CHRISTOPHER (contact); VENTERS, BRYAN J |
EPICYPHER, INC. |
View publication |
Active |
Semi-permeable capsules for high-throughput single cell multi-omics |
HG012771 |
KLEIN, ALLON MOSHE |
HARVARD MEDICAL SCHOOL |
View publication |
Active |
Telomere-to-telomere assemblies of human genomes |
HG011274 |
MIGA, KAREN HAYDEN |
UNIVERSITY OF CALIFORNIA SANTA CRUZ |
View publication |
Active |
Development of an Accurate, Long and Fast DNA Synthesis Device |
HG012278 |
PREDKI, PAUL F |
IRIDIA, INC. |
View publication |
Active |
Long-read single-molecule protein sequencing on an array of unfoldase-coupled nanopores |
HG012545 |
NIVALA, JEFFREY MATTHEW |
UNIVERSITY OF WASHINGTON |
View publication |
Active |
Single-molecule protein sequencing by iterative isolation and identification of N-terminal amino acids |
HG012563 |
ESTANDIAN, DANIEL MASAO |
GLYPHIC BIOTECHNOLOGIES, INC. |
View publication |
Active |
Single Molecule Protein Sequencing using Nanopores and Deep-UV Raman Spectroscopy |
HG012549 |
FREEDMAN, KEVIN |
UNIVERSITY OF CALIFORNIA RIVERSIDE |
View publication |
Active |
Towards Single-Molecule Protein Sequencing with Nanopores |
HG012544 |
GUNDLACH, JENS (contact); DEKKER, CEES |
UNIVERSITY OF WASHINGTON |
View publication |
Active |
Enzymeless, controlled electrostatic ratcheting in solid-state nanopores |
HG012413 |
SHEPARD, KENNETH L (contact); DRNDIC, MARIJA |
COLUMBIA UNIV NEW YORK MORNINGSIDE |
View publication |
Active |
Direct Electrical Measurement of Proteasome Activity for Single-Molecule Protein Sequencing |
HG012538 |
LINDSAY, STUART |
ARIZONA STATE UNIVERSITY-TEMPE CAMPUS |
View publication |
Active |
Advanced Parallel Readers for DNA Sequencing Through a 2D Nanopore |
HG012395 |
DRNDIC, MARIJA |
UNIVERSITY OF PENNSYLVANIA |
View publication |
Active |
Novel Chemical Probes for Sequencing Multiple DNA Modifications at Single-Nucleotide Resolution |
HG012412 |
ZHAO, LINLIN |
UNIVERSITY OF CALIFORNIA RIVERSIDE |
View publication |
Active |
Dual Reader Protein Sequencing |
HG012559 |
ERVIN, ERIC |
ELECTRONIC BIOSCIENCES, INC. |
View publication |
Active |
Two readers for RNA |
HG012364 |
SCHIBEL, ANNA |
ELECTRONIC BIOSCIENCES, INC. |
View publication |
Active |
Nanoscale Tools for Inosine Sequencing |
HG012409 |
ERVIN, ERIC |
ELECTRONIC BIOSCIENCES, INC. |
View publication |
Active |
Methods for Mapping Genetic Regulatory Elements in Single Cells and Single Molecules |
HG012383 |
STREETS, AARON |
UNIVERSITY OF CALIFORNIA BERKELEY |
View publication |
Active |
Multiplexed In Vivo DNA Assembly |
HG011676 |
LEVY, SASHA F (contact); SHERLOCK, GAVIN J |
STANFORD UNIVERSITY |
View publication |
Active |
High-throughput analysis of the effects of gene promoters and chromosomal environments on single-cell gene expression |
HG012304 |
COHEN, BARAK A |
WASHINGTON UNIVERSITY |
View publication |
Active |
A scalable kit-based assay for multi-omic analyses of transcriptional protein binding and chromatin interactions from ultra-low input frozen and FFPE samples at single-cell resolution |
HG011897 |
SCHMITT, ANTHONY |
ARIMA GENOMICS, INC. |
View publication |
Active |
Tagmentation-based Indexing for Methylation Sequencing as a novel method of high-throughput methylation clock measurement |
HG011850 |
SINCLAIR, DAVID A |
HARVARD MEDICAL SCHOOL |
View publication |
Active |
Bacteriophage Mu as Tool to Study Genome Organization in Bacteria and Eukaryotes |
HG011838 |
HARSHEY, RASIKA M (contact); FREDDOLINO, PETER L |
UNIVERSITY OF TEXAS, AUSTIN |
View publication |
Active |
High-throughput detection of transcriptomic and epitranscriptomic variation and kinetics using MarathonRT |
HG011868 |
PYLE, ANNA MARIE (contact); GRAVELEY, BRENTON R |
YALE UNIVERSITY |
View publication |
Active |
STAMP technology to enable single-cell and isoform-sensitive detection of RBP sites |
HG011864 |
YEO, EUGENE WEI-MING |
UNIVERSITY OF CALIFORNIA, SAN DIEGO |
View publication |
Active |
High-throughput development and characterization of compact tools for transcriptional and chromatin perturbations |
HG011866 |
BINTU, LACRAMIOARA (contact); BASSIK, MICHAEL C |
STANFORD UNIVERSITY |
View publication |
Active |
Ion Fountain Nanopore Readers for High-Resolution DNA and RNA Sequencing |
HG011689 |
WANUNU, MENI |
NORTHEASTERN UNIVERSITY |
View publication |
Active |
Nanopore based profiling of epigenetic state |
HG009190 |
TIMP, WINSTON GEORGE |
JOHNS HOPKINS UNIVERSITY |
View publication |
Active |
Protein tagging at scale to enable functional genomic studies |
HG011855 |
CHAVEZ, ALEJANDRO |
COLUMBIA UNIVERSITY HEALTH SCIENCES |
View publication |
Active |
Versatile, exponentially scalable methods for single cell molecular profiling |
HG010632 |
SHENDURE, JAY ASHOK (contact); TRAPNELL, BRUCE COLSTON |
UNIVERSITY OF WASHINGTON |
View publication |
Active |
Development of methods for multi-omic analysis of DNA methylation and chromatin architecture in single cells |
HG010634 |
ECKER, JOSEPH R (contact); DIXON, JESSE R |
SALK INSTITUTE FOR BIOLOGICAL STUDIES |
View publication |
Active |
Non-destructive epigenetic sequencing with DNA deaminase enzymes |
HG010646 |
KOHLI, RAHUL MANU (contact); WU, HAO |
UNIVERSITY OF PENNSYLVANIA |
View publication |
Active |
A single cell spatial genomics platform for multi-modal characterization of tissue organization |
HG010647 |
CHEN, FEI (contact); MACOSKO, EVAN Z |
BROAD INSTITUTE, INC. |
View publication |
Active |
Integrative single-cell spatial genomic, transcriptomic, and epigenetic imaging in mammalian tissue |
HG011245 |
WANG, SIYUAN |
YALE UNIVERSITY |
View publication |
Active |
Mapping gene-by-environment interactions using multiplexed single cell RNA-sequencing |
HG011239 |
YE, CHUN JIMMIE |
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO |
View publication |
Active |
Automated CRISPR Enabled DNA Synthesis (CEDS) |
HG011675 |
LYNCH, MICHAEL DAVID |
DUKE UNIVERSITY |
View publication |
Active |
Synthesis and non-chromatographic purification of long RNA oligonucleotides containing naturally occurring modification |
HG012257 |
ROYZEN, MAKSIM |
STATE UNIVERSITY OF NEW YORK AT ALBANY |
View publication |
Active |
GenSyn: A Cycle for Serial Assembly of Very Large DNA Molecules |
HG012281 |
SCHWARTZ, DAVID C |
UNIVERSITY OF WISCONSIN-MADISON |
View publication |
Active |
Enzymatic Synthesis of RNA |
HG011669 |
BENNER, STEVEN A (contact); POMERANTZ, RICHARD T |
FOUNDATION FOR APPLIED MOLECULAR EVOLUTION |
View publication |
Active |
A low-cost benchtop oligonucleotide synthesizer using inkjet enzymatic DNA synthesis |
HG011736 |
HORGAN, ADRIAN |
DNA SCRIPT |
View publication |
Active |
Conductance Fluctuations: A New Approach to Sequencing? |
HG010522 |
LINDSAY, STUART |
ARIZONA STATE UNIVERSITY-TEMPE CAMPUS |
View publication |
Active |
High Accuracy Nanopore Sequencing |
HG005115 |
GUNDLACH, JENS |
UNIVERSITY OF WASHINGTON |
View publication |
Active |
Direct Determination of Multiple Specific Forms of DNA Chemical Modifications in Human Genome |
HG011095 |
FANG, GANG |
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI |
View publication |
Active |
Direct nanopore detection of modified RNA to probe structure and dynamics |
HG010538 |
TIMP, WINSTON GEORGE |
JOHNS HOPKINS UNIVERSITY |
View publication |
Active |
Exploring 3Dpol for RNA sequencing in real time |
HG011120 |
HOU, YA-MING |
THOMAS JEFFERSON UNIVERSITY |
View publication |
Active |
Single-cell direct RNA sequencing using electrical zero-mode waveguides and engineered reverse transcriptases |
HG011087 |
WANUNU, MENI |
NORTHEASTERN UNIVERSITY |
View publication |
Active |
Sequencing by Direct Electrical Measurements of Polymerase Fluctuations |
HG011079 |
LINDSAY, STUART |
ARIZONA STATE UNIVERSITY-TEMPE CAMPUS |
View publication |
Active |
Improving biological nanopores for precision nucleic acid sequencing using a computational microscope |
HG011741 |
AKSIMENTIEV, ALEKSEI (contact); CHEN, MIN |
UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN |
View publication |
Active |
Single-Molecule Electronic Nucleic Acid Sequencing-by-Synthesis Using Novel Tagged Nucleotides and Nanopore Constructs |
HG010514 |
JU, JINGYUE (contact); CHURCH, GEORGE M; KALACHIKOV, SERGEY |
COLUMBIA UNIV NEW YORK MORNINGSIDE |
View publication |
Active |
Genome Technologies Coordinating Center |
HG011735 |
ADAMS, MARK D |
JACKSON LABORATORY |
View publication |
Active |
A single-strand ligation approach for concomitant DNA and RNA next-generation sequencing from low abundance inputs |
HG011877 |
RAO, VARSHA |
CLARET BIOSCIENCE, LLC |
View publication |
Complete |
RNA targeting tools with novel specific RNA-guided RNA-targeting CRISPR effectors |
HG011857 |
GOOTENBERG, JONATHAN SAMUEL (contact); ABUDAYYEH, OMAR O |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
View publication |
Complete |
Development of efficient quantitative chromatin profiling in kit and high-throughput formats |
HG010640 |
VENTERS, BRYAN J (contact); KEOGH, MICHAEL-CHRISTOPHER |
EPICYPHER, INC. |
View publication |
Complete |
Arrayed single-cell readout of pooled genetic perturbation libraries |
HG009283 |
BLAINEY, PAUL CLARK |
BROAD INSTITUTE, INC. |
View publication |
Complete |
Next-generation Functional Genetic Screening of Un-screenable Traits |
HG009285 |
MALI, PRASHANT (contact); TAMAYO, PABLO ; ZHANG, KUN |
UNIVERSITY OF CALIFORNIA, SAN DIEGO |
View publication |
Complete |
Programmable RNA-targeting tools |
HG009761 |
ZHANG, FENG |
BROAD INSTITUTE, INC. |
View publication |
Complete |
A transposase system for integrative ChIP-exo and ATAC-seq analysis at single-cell resolution |
HG010211 |
ZEITLINGER, JULIA |
STOWERS INSTITUTE FOR MEDICAL RESEARCH |
View publication |
Complete |
AVATAR: highly parallel analysis of variation in transcription factors and their DNA binding sites |
HG010200 |
BULYK, MARTHA L |
BRIGHAM AND WOMEN’S HOSPITAL |
View publication |
Complete |
Massively Parallel Single Cell Detection of Rare Variants with Split-Pool Combinatorial Indexing |
HG011229 |
KENNEDY, SCOTT ROBERT (contact); SEELIG, GEORG |
UNIVERSITY OF WASHINGTON |
View publication |
Complete |
Circular RNA as a platform for genome-wide microRNA sponge libraries |
HG011214 |
PICKERING, BRIAN FREDERICK |
CHIMERNA THERAPEUTICS INC. |
View publication |
Complete |
Orthocoding for Spatial Sequencing |
HG011231 |
SALZMAN, JULIA; FORDYCE, POLLY MORRELL; ROHATGI, RAJAT |
STANFORD UNIVERSITY |
View publication |
Complete |
Drop-BS: high-throughput single-cell bisulfite sequencing on a microfluidic droplet platform |
HG010195 |
LU, CHANG |
VIRGINIA POLYTECHNIC INST AND ST UNIV |
View publication |
Complete |
TempO-Seq Profiling of RNA Epitranscriptomic Modifications |
HG009763 |
SELIGMANN, BRUCE E. |
BIOSPYDER TECHNOLOGIES, INC. |
View publication |
Complete |
Epi-seq: Multiplexed ChIP-seq for personalized medicine and drug discovery |
HG010237 |
JELINEK, MARY ANNE |
ACTIVE MOTIF, INC. |
View publication |
Complete |
DNA barcoding via multi-scan and step control in dual-pore tug-of-war |
HG011236 |
REISNER, WALTER (contact); DUNBAR, WILLIAM BRUCE; SLADEK, ROBERT |
MCGILL UNIVERSITY |
View publication |
Complete |
On-site, high-fidelity target sequencing and absolute quantitation for HIV-1 surveillance |
HG010318 |
KIM, SANGGU |
OHIO STATE UNIVERSITY |
View publication |
Complete |
Development of a Fully Enzymatic Oligonucleotide Synthesis Cycle by Engineered Template Independent Polymerases and a Novel Phosphate dNTP Blocking Group |
HG011679 |
SAMMOND, DEANNE WALLANDER (contact); PAUL, NATASHA |
MOLECULAR ASSEMBLIES, INC. |
View publication |
Complete |